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Brook Andrews

Brook Andrews

Partner

Meridian
1320 Main Street
17th Floor
Columbia, SC 29201
T 803.255.5508
The McPherson Building
901 15th Street, NW
Suite 1200
Washington, D.C., 20005
T 202.689.2800
F 202.689.2860
brook.andrews@nelsonmullins.com
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Brook Andrews is a seasoned litigator, trial lawyer, and crisis manager who represents companies, executives, and healthcare organizations in government investigations, regulatory enforcement matters, internal investigations, and high-stakes litigation. Drawing on more than 15 years of leadership at the U.S. Department of Justice, Brook helps clients navigate complex disputes involving the Department of Justice, HHS-OIG,...

Brook Andrews is a seasoned litigator, trial lawyer, and crisis manager who represents companies, executives, and healthcare organizations in government investigations, regulatory enforcement matters, internal investigations, and high-stakes litigation. Drawing on more than 15 years of leadership at the U.S. Department of Justice, Brook helps clients navigate complex disputes involving the Department of Justice, HHS-OIG, FTC, SEC, FDIC, DEA, State Attorneys General, and other federal and state regulators.

Brook joined Nelson Mullins after serving as Acting United States Attorney for the District of South Carolina, where he oversaw all federal criminal and civil enforcement activity in the state. In that role, he led approximately 140 prosecutors, civil litigators, and support personnel across four offices and was responsible for some of the government's most significant investigations, prosecutions, and civil enforcement initiatives.

Today, Brook represents clients nationwide in False Claims Act investigations and litigation, healthcare fraud and compliance matters, government investigations, civil investigative demands (CIDs), grand jury investigations, internal investigations, and complex commercial disputes. He regularly advises healthcare providers, insurers, pharmacies, technology companies, financial institutions, and other businesses facing regulatory scrutiny, enforcement risk, and business-critical crises. His experience includes obtaining favorable resolutions in government investigations, defending clients in parallel civil and regulatory proceedings, and securing injunctive relief against unlawful or arbitrary government action.

Prior to his service as Acting U.S. Attorney, Brook served as First Assistant U.S. Attorney and Deputy Criminal Chief, supervising the White Collar and General Crimes Section and overseeing many of the office's most complex and high-profile matters. During his DOJ career, he investigated and prosecuted a broad range of cases involving healthcare fraud, securities fraud, public corruption, defense procurement fraud, cybercrime, money laundering, national security matters, and other significant white-collar offenses. He also handled and supervised numerous corporate criminal resolutions, False Claims Act investigations, civil settlements, jury trials, and appeals.

Before entering federal service, Brook practiced at a major law firm where he represented State Attorneys General in complex multistate litigation and consumer protection matters, including some of the nation's largest coordinated enforcement actions.

Brook is an accomplished public speaker who regularly presents to bar and industry associations, clients, and law students; he served on the faculty of the University of South Carolina School of Law for nearly 10 years as a professor of moot court and appellate advocacy.

Brook Andrews

FTC, SEC, FDIC, DEA, State Attorneys General, and other federal and state regulators.

Brook joined Nelson Mullins after serving as Acting United States Attorney for the District of South Carolina, where he oversaw all federal criminal and civil enforcement activity in the state. In that role, he led approximately 140 prosecutors, civil litigators, and support personnel across four offices and was responsible for some of the government's most significant investigations, prosecutions, and civil enforcement initiatives.

Today, Brook represents clients nationwide in False Claims Act investigations and litigation, healthcare fraud and compliance matters, government investigations, civil investigative demands (CIDs), grand jury investigations, internal investigations, and complex commercial disputes. He regularly advises healthcare providers, insurers, pharmacies, technology companies, financial institutions, and other businesses facing regulatory scrutiny, enforcement risk, and business-critical crises. His experience includes obtaining favorable resolutions in government investigations, defending clients in parallel civil and regulatory proceedings, and securing injunctive relief against unlawful or arbitrary government action.

Prior to his service as Acting U.S. Attorney, Brook served as First Assistant U.S. Attorney and Deputy Criminal Chief, supervising the White Collar and General Crimes Section and overseeing many of the office's most complex and high-profile matters. During his DOJ career, he investigated and prosecuted a broad range of cases involving healthcare fraud, securities fraud, public corruption, defense procurement fraud, cybercrime, money laundering, national security matters, and other significant white-collar offenses. He also handled and supervised numerous corporate criminal resolutions, False Claims Act investigations, civil settlements, jury trials, and appeals.

Before entering federal service, Brook practiced at a major law firm where he represented State Attorneys General in complex multistate litigation and consumer protection matters, including some of the nation's largest coordinated enforcement actions.

Brook is an accomplished public speaker who regularly presents to bar and industry associations, clients, and law students; he served on the faculty of the University of South Carolina School of Law for nearly 10 years as a professor of moot court and appellate advocacy.

Experience

The following is a selected sampling of matters and is provided for informational purposes only. Past success does not indicate the likelihood of success in any future matter.

Representative Matters 

  • Defends companies and executives in government investigations, enforcement actions, and regulatory proceedings involving federal and state agencies including the U.S. Department of Justice (DOJ), Securities and Exchange Commission (SEC), Department of Health and Human Services Office of Inspector General (HHS-OIG), Federal Trade Commission (FTC), Federal Deposit Insurance Corporation (FDIC), Drug Enforcement Administration (DEA), and State Attorneys General.
  • Represents healthcare providers, insurers, and other businesses in False Claims Act investigations and litigation nationwide, including matters that concluded with government declinations and no further enforcement action.
  • Leads responses to civil investigative demands (CIDs), grand jury subpoenas, administrative subpoenas, and other compulsory process issued by federal and state enforcement agencies.
  • Obtains emergency and permanent injunctive relief against federal agencies and government entities engaging in unlawful, arbitrary, or capricious agency action.
  • Represents clients in matters involving parallel civil, criminal, and regulatory proceedings, coordinating litigation strategy, government engagement, internal investigations, and crisis management efforts.
  • Conducts internal investigations involving allegations of fraud, healthcare misconduct, financial improprieties, compliance failures, employee wrongdoing, and other matters presenting substantial regulatory or enforcement risk.
  • Advises healthcare providers, payors, pharmacies, and healthcare technology companies regarding False Claims Act exposure, Anti-Kickback Statute compliance, reimbursement disputes, audits, overpayment issues, and government investigations.
  • Defends businesses facing allegations of fraud, wire fraud, RICO violations, unfair business practices, and other high-stakes commercial disputes in state and federal courts.
  • Counsels boards of directors, executives, and compliance professionals regarding regulatory risk, enforcement strategy, voluntary disclosures, remediation efforts, and interactions with prosecutors, regulators, and law-enforcement agencies.
  • Represents clients responding to cybersecurity incidents, business-email-compromise schemes, wire-transfer fraud, data-security events, and other corporate crises requiring immediate legal and strategic response.
  • Represents clients in federal and state appellate proceedings involving significant regulatory, constitutional, administrative law, and commercial issues.
  • Provides pro bono representation in appellate and post-conviction matters, including petitions for certiorari, post-conviction relief proceedings, and other matters involving significant constitutional questions.

Previous Professional Experience

  • Adjunct Professor of Appellate Advocacy, University of South Carolina Joseph F. Rice School of Law (2018-2026)
  • United States Attorney’s Office for the District of South Carolina
    • Acting United States Attorney (2025)
    • First Assistant United States Attorney (2022 – 2025)
    • Deputy Criminal Chief, White Collar and General Crimes Section (2022)
    • Assistant U.S. Attorney, White Collar and General Crimes Section (2018 – 2022), Appellate Division (2018 – 2022), Affirmative Civil Enforcement Unit (2015 – 2018)
  • Assistant U.S. Attorney, Western District of North Carolina (2014 – 2015)
  • Litigation Associate, national law firm (2012 – 2014)
  • Trial Attorney, United States Department of Justice, Environment and Natural Resources Division (2009 – 2012)

Publications

The following is a selected sampling of matters and is provided for informational purposes only. Past success does not indicate the likelihood of success in any future matter.

Representative Matters 

  • Defends companies and executives in government investigations, enforcement actions, and regulatory proceedings involving federal and state agencies including the U.S. Department of Justice (DOJ), Securities and Exchange Commission (SEC), Department of Health and Human Services Office of Inspector General (HHS-OIG), Federal Trade Commission (FTC), Federal Deposit Insurance Corporation (FDIC), Drug Enforcement Administration (DEA), and State Attorneys General.
  • Represents healthcare providers, insurers, and other businesses in False Claims Act investigations and litigation nationwide, including matters that concluded with government declinations and no further enforcement action.
  • Leads responses to civil investigative demands (CIDs), grand jury subpoenas, administrative subpoenas, and other compulsory process issued by federal and state enforcement agencies.
  • Obtains emergency and permanent injunctive relief against federal agencies and government entities engaging in unlawful, arbitrary, or capricious agency action.
  • Represents clients in matters involving parallel civil, criminal, and regulatory proceedings, coordinating litigation strategy, government engagement, internal investigations, and crisis management efforts.
  • Conducts internal investigations involving allegations of fraud, healthcare misconduct, financial improprieties, compliance failures, employee wrongdoing, and other matters presenting substantial regulatory or enforcement risk.
  • Advises healthcare providers, payors, pharmacies, and healthcare technology companies regarding False Claims Act exposure, Anti-Kickback Statute compliance, reimbursement disputes, audits, overpayment issues, and government investigations.
  • Defends businesses facing allegations of fraud, wire fraud, RICO violations, unfair business practices, and other high-stakes commercial disputes in state and federal courts.
  • Counsels boards of directors, executives, and compliance professionals regarding regulatory risk, enforcement strategy, voluntary disclosures, remediation efforts, and interactions with prosecutors, regulators, and law-enforcement agencies.
  • Represents clients responding to cybersecurity incidents, business-email-compromise schemes, wire-transfer fraud, data-security events, and other corporate crises requiring immediate legal and strategic response.
  • Represents clients in federal and state appellate proceedings involving significant regulatory, constitutional, administrative law, and commercial issues.
  • Provides pro bono representation in appellate and post-conviction matters, including petitions for certiorari, post-conviction relief proceedings, and other matters involving significant constitutional questions.

Previous Professional Experience

  • Adjunct Professor of Appellate Advocacy, University of South Carolina Joseph F. Rice School of Law (2018-2026)
  • United States Attorney’s Office for the District of South Carolina
    • Acting United States Attorney (2025)
    • First Assistant United States Attorney (2022 – 2025)
    • Deputy Criminal Chief, White Collar and General Crimes Section (2022)
    • Assistant U.S. Attorney, White Collar and General Crimes Section (2018 – 2022), Appellate Division (2018 – 2022), Affirmative Civil Enforcement Unit (2015 – 2018)
  • Assistant U.S. Attorney, Western District of North Carolina (2014 – 2015)
  • Litigation Associate, national law firm (2012 – 2014)
  • Trial Attorney, United States Department of Justice, Environment and Natural Resources Division (2009 – 2012)

Publications

Media

Visit Insights

Recognitions

The bar rules of some states require that the standards for an attorney's inclusion in certain public accolades or recognitions be provided. When such accolades or recognitions are listed, a hyperlink is provided that leads to a description of the respective selection methodology.

  • The Legal 500 US Elite – Southeast, White Collar Crime (2026)
  • United States Attorney’s Special Commendation for Trial Work (2024)
  • United States Attorney’s Special Commendation for Litigation (2023)
  • United States Attorney’s Award (2021, 2017)
  • United States Department of Justice Outstanding Performance Award (2012, 2011)

Professional Activities

  • American Bar Association
  • Federal Bar Association
  • District of Columbia Bar Association
  • South Carolina Bar Association
  • American Health Law Association
  • John Belton O’Neall Inn of Court

Leadership

  • Aspen Global Leadership Network, Liberty Fellow (2026)
  • Federal Bar Association - South Carolina Chapter, Board Member (2025 – present)
  • Transitions Homeless Center, Board Member (2025 – present)
  • Downtown Presbyterian Church, Elder (2025 – present)
  • Achieve Columbia, Board Member (2016-2018)
  • South Carolina Bar Leadership Academy (2017)
  • South Carolina Bar House of Delegates, Delegate (Out of State Representative, 2011-2012; Fifth Circuit Representative, 2015-2016)

Brook Andrews is a seasoned litigator, trial lawyer, and crisis manager who represents companies, executives, and healthcare organizations in government investigations, regulatory enforcement matters, internal investigations, and high-stakes litigation. Drawing on more than 15 years of leadership at the U.S. Department of Justice, Brook helps clients navigate complex disputes involving the Department of Justice, HHS-OIG,... FTC, SEC, FDIC, DEA, State Attorneys General, and other federal and state regulators.

Brook joined Nelson Mullins after serving as Acting United States Attorney for the District of South Carolina, where he oversaw all federal criminal and civil enforcement activity in the state. In that role, he led approximately 140 prosecutors, civil litigators, and support personnel across four offices and was responsible for some of the government's most significant investigations, prosecutions, and civil enforcement initiatives.

Today, Brook represents clients nationwide in False Claims Act investigations and litigation, healthcare fraud and compliance matters, government investigations, civil investigative demands (CIDs), grand jury investigations, internal investigations, and complex commercial disputes. He regularly advises healthcare providers, insurers, pharmacies, technology companies, financial institutions, and other businesses facing regulatory scrutiny, enforcement risk, and business-critical crises. His experience includes obtaining favorable resolutions in government investigations, defending clients in parallel civil and regulatory proceedings, and securing injunctive relief against unlawful or arbitrary government action.

Prior to his service as Acting U.S. Attorney, Brook served as First Assistant U.S. Attorney and Deputy Criminal Chief, supervising the White Collar and General Crimes Section and overseeing many of the office's most complex and high-profile matters. During his DOJ career, he investigated and prosecuted a broad range of cases involving healthcare fraud, securities fraud, public corruption, defense procurement fraud, cybercrime, money laundering, national security matters, and other significant white-collar offenses. He also handled and supervised numerous corporate criminal resolutions, False Claims Act investigations, civil settlements, jury trials, and appeals.

Before entering federal service, Brook practiced at a major law firm where he represented State Attorneys General in complex multistate litigation and consumer protection matters, including some of the nation's largest coordinated enforcement actions.

Brook is an accomplished public speaker who regularly presents to bar and industry associations, clients, and law students; he served on the faculty of the University of South Carolina School of Law for nearly 10 years as a professor of moot court and appellate advocacy.

Experience

The following is a selected sampling of matters and is provided for informational purposes only. Past success does not indicate the likelihood of success in any future matter.

Representative Matters 

  • Defends companies and executives in government investigations, enforcement actions, and regulatory proceedings involving federal and state agencies including the U.S. Department of Justice (DOJ), Securities and Exchange Commission (SEC), Department of Health and Human Services Office of Inspector General (HHS-OIG), Federal Trade Commission (FTC), Federal Deposit Insurance Corporation (FDIC), Drug Enforcement Administration (DEA), and State Attorneys General.
  • Represents healthcare providers, insurers, and other businesses in False Claims Act investigations and litigation nationwide, including matters that concluded with government declinations and no further enforcement action.
  • Leads responses to civil investigative demands (CIDs), grand jury subpoenas, administrative subpoenas, and other compulsory process issued by federal and state enforcement agencies.
  • Obtains emergency and permanent injunctive relief against federal agencies and government entities engaging in unlawful, arbitrary, or capricious agency action.
  • Represents clients in matters involving parallel civil, criminal, and regulatory proceedings, coordinating litigation strategy, government engagement, internal investigations, and crisis management efforts.
  • Conducts internal investigations involving allegations of fraud, healthcare misconduct, financial improprieties, compliance failures, employee wrongdoing, and other matters presenting substantial regulatory or enforcement risk.
  • Advises healthcare providers, payors, pharmacies, and healthcare technology companies regarding False Claims Act exposure, Anti-Kickback Statute compliance, reimbursement disputes, audits, overpayment issues, and government investigations.
  • Defends businesses facing allegations of fraud, wire fraud, RICO violations, unfair business practices, and other high-stakes commercial disputes in state and federal courts.
  • Counsels boards of directors, executives, and compliance professionals regarding regulatory risk, enforcement strategy, voluntary disclosures, remediation efforts, and interactions with prosecutors, regulators, and law-enforcement agencies.
  • Represents clients responding to cybersecurity incidents, business-email-compromise schemes, wire-transfer fraud, data-security events, and other corporate crises requiring immediate legal and strategic response.
  • Represents clients in federal and state appellate proceedings involving significant regulatory, constitutional, administrative law, and commercial issues.
  • Provides pro bono representation in appellate and post-conviction matters, including petitions for certiorari, post-conviction relief proceedings, and other matters involving significant constitutional questions.

Previous Professional Experience

  • Adjunct Professor of Appellate Advocacy, University of South Carolina Joseph F. Rice School of Law (2018-2026)
  • United States Attorney’s Office for the District of South Carolina
    • Acting United States Attorney (2025)
    • First Assistant United States Attorney (2022 – 2025)
    • Deputy Criminal Chief, White Collar and General Crimes Section (2022)
    • Assistant U.S. Attorney, White Collar and General Crimes Section (2018 – 2022), Appellate Division (2018 – 2022), Affirmative Civil Enforcement Unit (2015 – 2018)
  • Assistant U.S. Attorney, Western District of North Carolina (2014 – 2015)
  • Litigation Associate, national law firm (2012 – 2014)
  • Trial Attorney, United States Department of Justice, Environment and Natural Resources Division (2009 – 2012)

Publications

Education

  • University of South Carolina Joseph F. Rice School of Law, JD (2007)
    • Order of the Barristers 
    • Compleat Lawyer Award, Bronze Medallion
    • Editor, South Carolina Law Review
    • Moot Court Bar National Team
    • Chair, Honor Council
    • President, Public Interest Law Society
  • George Washington University, MA, Legislative Affairs (2004)
  • Davidson College, BA, History (2001)

Admissions

  • South Carolina
  • District of Columbia
  • U.S. Court of Appeals for the District of Columbia Circuit
  • U.S. Court of Appeals for the Fourth Circuit
  • U.S. District Court for the District of South Carolina
  • U.S. Court of Federal Claims
  • U.S. District Court for the District of Columbia
  • U.S. Court of Appeals for the Federal Circuit
  • U.S. Supreme Court

Clerkships

  • Law Clerk, The Honorable Jean H. Toal, Former Chief Justice, Supreme Court of South Carolina
  • Law Clerk, The Honorable Margaret B. Seymour, U.S. District Court for the District of South Carolina

Practice Areas

Industries

The bar rules of some states require that the standards for an attorney's inclusion in certain public accolades or recognitions be provided. When such accolades or recognitions are listed, a hyperlink is provided that leads to a description of the respective selection methodology.

  • The Legal 500 US Elite – Southeast, White Collar Crime (2026)
  • United States Attorney’s Special Commendation for Trial Work (2024)
  • United States Attorney’s Special Commendation for Litigation (2023)
  • United States Attorney’s Award (2021, 2017)
  • United States Department of Justice Outstanding Performance Award (2012, 2011)
  • American Bar Association
  • Federal Bar Association
  • District of Columbia Bar Association
  • South Carolina Bar Association
  • American Health Law Association
  • John Belton O’Neall Inn of Court
  • Aspen Global Leadership Network, Liberty Fellow (2026)
  • Federal Bar Association - South Carolina Chapter, Board Member (2025 – present)
  • Transitions Homeless Center, Board Member (2025 – present)
  • Downtown Presbyterian Church, Elder (2025 – present)
  • Achieve Columbia, Board Member (2016-2018)
  • South Carolina Bar Leadership Academy (2017)
  • South Carolina Bar House of Delegates, Delegate (Out of State Representative, 2011-2012; Fifth Circuit Representative, 2015-2016)